• Value in integrity, equality, and solidarity;
  • Advance exchange in science and research;
  • Promote communication, collaboration and connection;
  • Establish platforms in developing career and probing the essence of life;
  • Reach out to community and public.

2010-03-31

PUPA SAPA-GP Career Planning Workshop

You are cordially invited to Greater Philadelphia Area Career Planning Workshop on April 10, 2010 (Saturday), 10 am – 1 pm at Claudia Cohen Hall G17 Auditorium, University of Pennsylvania (249 South 36th Street, Philadelphia PA 19104, local map is as below with nearby parking lots highlighted).  The seminar features a panel of 3 industry executives with professional leadership in pharmaceutical R&D, technology transfer and marketing. The workshop is aimed to help students, postdocs and professionals get well prepared for the workplace and to live fulfilling careers.  

The seminar series is open to the public and is jointly organized by Sino-American Pharmaceutical Professional Association and Peking University Philadelphia Alumni Penn Office, sponsored by SASgov at University of Pennsylvania. It is a great opportunity for students, postdocs, and scholars in the greater Philadelphia area to network and learn from veteran leaders from the industry, and to develop a successful career.


Time:   10 am – 1 pm, Saturday, April 10, 2010
Place:  Claudia Cohen Hall G17 Auditorium, University of Pennsylvania

249 South 36th Street, Philadelphia PA 19104 
 http://www.facilities.upenn.edu/map.php

 

Target audience: Graduate students, postdocs, and professionals in academia and industry

Agenda

9:30 am -10:00 am On-site registration (free), Refreshments

10:00 am -10:10 am Welcome

10:10 am -11:10 am Speaker presentation

Liu, Mike     MD. PhD. Senior Clinical Development Manager,
Global Clinical Development Center,  GSK Biologicals
 
Chen, Erli   PhD.   Director of Nanotechnology Licensing,
 Center for Technology Transfer, University of Pennsylvania.

Wang, Mingbo  MBA.   Global Strategic Marketing at Johnson & Johnson

Li, Yunsong (Frank)   PhD.   Senior Research Biochemist, Merck

11:10 am -12:30 pm Q & A and Panel discussion

12:30 pm   Conclusion


Co-Organizers:
• SAPA-GP: Sino-American Pharmaceutical Professionals Association – Greater Philadelphia Chapter
• PUPA: Peking University Philadelphia Association
Sponsor:   GAPSA, University of Pennsylvania

Please see the attachment for more information. Please reply to yuting_Zhao@hotmail.com to register the event (free).



2010-03-18

费城科学论坛系列讲座/PSF series talk: 5:30-7:30pm Thur (Mar. 25) at CRB Room 302

Please join us for Philadelphia Science Forum series talk 5:30-7:30pm Thur(Mar. 25) at CRB Room 302

Title: Principles of Clinical Trials and Drug Development


Speaker: Di WU, PhD, FCP

Laboratory for Applied PK/PD

Clinical Pharmacology & Therapeutics

The Children’s Hospital of Philadelphia

Kinetic Modeling and Simulation Institute of Translational Medicine and Therapeutics

University of Pennsylvania

Abstract: Basic concepts and principles of clinical trials and drug
development will be described and elucidated. FDA regulations for IND
and NDA applications will be addressed. Some concerns for drug
development would be discussed in the presentation. Audience will
obtain a generalized picture of clinical trial and drug development by
this seminar.


Snack and beverage will be served.

2010-03-01

费城科学论坛系列讲座/PSF series talk: 5:30-7:30pm Wednesday (March 3) at CRB Room 302

Please join us for the Philadelphia Science Forum series talk, 5:30-7:30pm Wednesday(March 3) at CRB Room 302.

Title: Seeking therapy for autoimmune diseases: from library screening to patient treatment

Speaker: Dr. Xuming Mao (Department of Dermatology, UPenn)

Abstract:  Autoimmune diseases occur when an overactive immune response attacks tissues or cells normally present in the human body. Pemphigus represents one of the autoimmune disorders that target only the skin and mucous membranes. It is a potentially fatal blistering disease characterized by autoantibodies against desmoglein (Dsg) cell adhesion proteins. To study the role of autoantibodies in pathogenesis and seek new specific treatments, we isolated lymphocytes from patients with pemphigus, followed by mRNAs to establish a cDNA expression library. Using antibody phage display, we have isolated repertoires of human anti-Dsg mAbs as single-chain variable-region fragments (scFvs) from a patient with active mucocutaneous pemphigus vulgaris.  Injection of these pathogenic but not the nonpathogenic antibodies reproduced blisters in animal models or in organ-cultured human skin. In vitro studies showed mAb causes rapid internalization of Dsg during assembly in skin epidermal cells. Furthermore, we found the pathogenic antibodies triggered activation of certain signaling pathways that may contribute to antibody-mediated pathogenecity. Our preliminary results have demonstrated that interference of antibody binding or subsequent activation of cell signaling will help us to identify targeted therapy of pemphigus in the future.

Snack and beverage will be served.